Platelet-rich plasma (PRP) therapy uses injections of a concentration of a patient’s own platelets to aid in the healing of injured tendons, ligaments, muscles and joints.
In this way, PRP injections use an individual patient's own healing system to improve musculoskeletal problems.
PRP injections are prepared by taking your own blood and running it through a centrifuge to concentrate the platelets. These activated platelets are then injected directly into your injured or diseased body tissue.
This releases growth factors that stimulate your body's ability to heal itself.
Ultrasound imaging is used to guide the injection.
Level I Evidence: High quality randomized trial or prospective study; testing of previously developed diagnostic criteria on consecutive patients; sensible costs and alternatives; values obtained from many studies with multiway sensitivity analyses; systematic review of Level I RCTs and Level I studies.
Administration of ACP improved WOMAC* scores by 78% from the baseline score versus only 7% for the placebo control group after 1 year. Furthermore, no adverse events for ACP treatment were reported. Therefore, the study conclusion is that ACP is safe and provides quantifiable benefits for pain relief and functional improvement with regard to knee OA. Other joints affected with OA may also benefit from this treatment.
* The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a widely used, proprietary set of standardized questions used by health professionals to evaluate the condition of patients with osteoarthritis of the knee and hip, including pain, stiffness, and physical functioning of the joints. It can be self-administered and was developed at Western Ontario and McMaster Universities in 1982.
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